Allograft Resources, a department of the UT Transplant Centera department of the UT Transplant CenterAllograft Resources

Medical Applications of Donated Tissues for Transplantation

 
EYE TISSUE
Donor Tissue: Eye
Transplanted Tissue: Sclera
Typical Applications: Repair eyelid, reinforce wall of eye.

Benefits to Recipients: Prevents blindness, restores vision.

 
Donor Tissue: Eye
Transplanted Tissue: Cornea
Typical Applications: Replace diseased or damaged cornea.

Benefits to Recipients: Prevents blindness, restores vision.

 
BONE TISSUE
Donor Tissue: Humerus
Transplanted Tissue: Whole, Proximal, Distal, Shaft
Typical Applications: Reconstruction related to trauma, tumors, degenerative diseases, and fractures.

Benefits to Recipients: Prevents amputation accelerates, promotes, and allows healing.

 
Donor Tissue: Humerus
Transplanted Tissue: Humeral Head
Typical Applications: Total hip revision.

Benefits to Recipients: Restores mobility.

 
Donor Tissue: Femur
Transplanted Tissue: Whole, Proximal, Distal, Shaft
Typical Applications: Reconstruction related to trauma, tumors, degenerative diseases, and fractures.

Benefits to Recipients: Prevents amputation accelerates, promotes, and allows healing.

 
Donor Tissue: Femur
Transplanted Tissue: Femoral Head
Typical Applications: Reconstruction of damaged acetabulum, supplement for small defects.

Benefits to Recipients: Restores mobility.

 
Donor Tissue: Femur
Transplanted Tissue: Dowel
Typical Applications: Cervical spinal fusion.

Benefits to Recipients: Prevents collapse of bone, reduces pain, reduces chance of nerve damage.

 
Donor Tissue: Femur
Transplanted Tissue: Cancellous
Typical Applications: Filling defects, augments prosthetic device implant.

Benefits to Recipients: Accelerates, promotes, and allows healing.

 
Donor Tissue: Tibia
Transplanted Tissue: Whole, Proximal, Distal, Shaft
Typical Applications: Reconstruction related to trauma, tumors, degenerative diseases, and fractures.

Benefits to Recipients: Prevents amputation accelerates, promotes, and allows healing.

 
Donor Tissue: Tibia
Transplanted Tissue: Cortical strut
Typical Applications: Augments large grafts and prosthetic implants.

Benefits to Recipients: Restores mobility, promotes healing.

 
Donor Tissue: Fibula
Transplanted Tissue: Fibular Shaft
Typical Applications: Repair of traumatic bone loss.

Benefits to Recipients: Restores mobility, promotes healing.

 
Donor Tissue: Ilia
Transplanted Tissue: Iliac crest wedge, ilium strip
Typical Applications: Spinal fusion.

Benefits to Recipients: Prevents further collapse of bone, reduces pain, reduces chance of nerve damage.

 
Donor Tissue: Ilia
Transplanted Tissue: Cortical cancellous
Typical Applications: Filling defects, augments prosthetic device implant.

Benefits to Recipients: Accelerates, promotes, and allows healing.

 
Donor Tissue: Acetabulum
Transplanted Tissue: Acetabulum
Typical Applications: Acetabular reconstruction.

Benefits to Recipients: Restores mobility.

 
Donor Tissue: Rib
Transplanted Tissue: Rib
Typical Applications: Mandible repair augment as a strut graft.

Benefits to Recipients: Restores normal facial appearance.

 
CARDIOVASCULAR TISSUES
Donor Tissue: Heart Valves
Transplanted Tissue: Aortic and Pulmonary Heart Valve
Typical Applications: Replacement for damaged heart valves.

Benefits to Recipients: No long-term anticoagulant therapy. Almost no rejection. Allows children to grow into graft (no second surgery for size). Graft doesn't calcify.

 
Donor Tissue: Saphenous Valves
Transplanted Tissue: Saphenous Vein
Typical Applications: CABG, below knee vascularization.

Benefits to Recipients: Vascularization, prevents amputation.

 
Donor Tissue: Thoracic Aorta
Transplanted Tissue: Thoracic Aorta
Typical Applications: Aortic patch grafts.

Benefits to Recipients: Superior to synthetic materials.

 
CONNECTIVE TISSUES
Donor Tissue: Patellar Tendon
Transplanted Tissue: Patellar Tendon
Typical Applications: Replace ACL, PCL.

Benefits to Recipients: Returns mobility, restores independence in activities of daily living.

 
Donor Tissue: Achilles' Tendon
Transplanted Tissue: Achilles' Tendon
Typical Applications: Replace PCL, used as rotator cuff, replace Achilles' tendon.

Benefits to Recipients: Returns mobility, restores independence in activities of daily living.

 
Donor Tissue: Cartilage
Transplanted Tissue: Cartilage
Typical Applications: Repair congenital and traumatic facial deformity

Benefits to Recipients: Restores normal facial appearance.

 
Donor Tissue: Fascia Lata
Transplanted Tissue: Fascia Lata
Typical Applications: Used as tendon to repair injury.

Benefits to Recipients: Returns mobility, restores independence in activities of daily living.

 
Donor Tissue: Rotator Cuff
Transplanted Tissue: Rotator Cuff
Typical Applications: Shoulder repair.

Benefits to Recipients: Independence in ADL's, mobility, and decreases joint pain, i.e. hip, knee, joint, wrist.

 
OTHER TISSUES
Donor Tissue: Nerve
Transplanted Tissue: Femoral, Sural Nerve
Typical Applications: Neurosurgery in wrist.

Benefits to Recipients: Restores feeling and function of the hand.

 
Donor Tissue: Pericardium
Transplanted Tissue: Pericardium
Typical Applications: Neurosurgery (as alternative to using dura mater).

Benefits to Recipients: Protective covering replacement.

 
Donor Tissue: Skin
Transplanted Tissue: Skin
Typical Applications: Grafts for burn victims.

Benefits to Recipients: Promotes healing, natural barrier to infection.

 

These examples are not meant to be all-inclusive.

This fact sheet prepared by Acorn, a national service provider to the donation and transplant community.