Charleen M. Moore, Ph.D., Professor
University of Tennessee
1971

(210) 567-3875
MOOREC@UTHSCSA.EDU

Dr. Moore participates in teaching Medical Gross Anatomy and Embryology to first year medical students and is director of the Medical School Enrichment Elective (ELEC 5022) and Graduate School elective, History of Anatomy (CSBL 5015), which includes a visit to the UTHSCSA, P.I. Nixon Medical History Library collection. CLICK HERE to view Photo Gallery of visit to P.I. Nixon Medical History Library.

She directs a course for fourth year medical students, History of Anatomy In Situ (CSBL 4024), which focuses on the reawakening and development of the study of anatomy in 14th-18th century Italy. This course includes a trip to Italy (Padua, Bologna, and Florence) to visit the oldest extant medical schools and anatomical dissecting theaters where this resurgence occurred. CLICK HERE to view CSBL 4024 Photo Gallery.

Dr. Moore also gives lectures in the area of human cytogenetics and participates in medical ethics courses. Related to her interest in the history of medicine, Dr. Moore has published articles on the intersection of art, anatomy and religion (Moore and Brown, 2004a and b).

Dr. Moore's research activities have centered on characterizing human cytogenetic abnormalities and carrying out comparative cytogenetics studies in primates and marsupials. Currently, her research focuses on problems in the area of aging. She has performed comparative cytogenetic studies in several primate species, including the baboon, macaque, and squirrel monkey. She has described analogous chromosomal rearrangements to human cytogenetic abnormalities in the macaque and baboon (Ruppenthal et al., 2004; Dudley et al., 2006; Howell et al., 2006; Moore et al. 2007b). She has also demonstrated the homology of the human karyotype with that of the baboon and rheboon (a rhesus monkey/baboon hybrid).

Current research activities include chromosome breakage studies in aging related to calorie restriction and to life span (Moore et al., 2007a), and identifying chromosomal abnormalities in baboons and rhesus macaques related to the development of spontaneous tumors (Moore et al., 2003; Moore et al., 2006), to environmental conditions (Frost et al., 2004), and to stillbirths.

Research Techniques:
GTG-banding
Fluorescent in situ hybridization (FISH)
Unbanded breakage studies

PUBLICATIONS:
Moore CM, Brown CM. (2007) Experiencing Body Worlds: voyeurism, education, or enlightenment?
J Med Humanit. 2007 Dec;28(4):231-54.

Moore CM, Dunn BG, McMahan CA, Lane MA, Roth GS, Ingram DK, Mattison JA: (2007) Effects of calorie restriction on chromosomal stability in rhesus monkeys (Macaca mulatta). AGE: J Am Aging Soc 2007a; 29:15-28.

Moore CM, Hubbard GB, Dick E, Dunn BG, Raveendran M, Rogers J, Williams V, Gomez JJ, Butler SD, Leland MM, Schlabritz-Loutsevitch NE. (2007) Trisomy 17 in a baboon (Papio hamadryas) with polydactyly, patent foramen ovale and pyelectasis. Am J Primatol. Oct;69(10):1105-18.

Howell KH, Hubbard GB, Moore CM, Dunn BG, von Kap-Herr C, Raveendran M, Rogers JA, Leland MM, Brasky KM, Nathanielsz PW, Schlabritz-Loutsevitch NE. (2006) Trisomy of chromosome 18 in the baboon (Papio hamadryas anubis). Cytogenet Genome Res. 112(1-2):76-81.

Moore CM, Hubbard GB, Leland MM, Dunn BG, Barrier BF, Siler-Khodr TM, Schlabritz-Loutsevitch NE. (2006) Primary amenorrhea associated with ovarian leiomyoma in a baboon (Papio hamadryas).J Am Assoc Lab Anim Sci. May;45(3):58-62.

Dudley CJ, Hubbard GB, Moore CM, Dunn BG, Raveendran M, Rogers J, Nathanielsz PW, McCarrey JR, Schlabritz-Loutsevitch NE. (2006) A male baboon (Papio hamadryas) with a mosaic 43,XXY/42,XY karyotype. Am J Med Genet A. Jan 1;140(1):94-7.

Frost PA, Hubbard GB, Dammann MJ, Snider CL, Moore CM, Hodara VL, Giavedoni LD, Rohwer R, Mahaney MC, Butler TM, Cummins LB, McDonald TJ, Nathanielsz PW, Schlabritz-Loutsevitch NE: (2004) White Monkey Syndrome in Infant Baboons (Papio species). J Med Primatol. Aug;33(4):197-213.

Moore CM, Brown CM: (2004) Gunther von Hagens and Body Worlds. Part 1. The Anatomist as Prosektor and Proplastiker. The Anatomical Record Part B: The New Anatomist Jan;276(1):8-14.

Moore CM, Brown CM: (2004) Gunther von Hagens and Body Worlds. Part 2. The Anatomist as Priest and Prophet. The Anatomical Record Part B: The New Anatomist Mar;277(1):14-20.

Ruppenthal GC, Moore CM, Best RG, Walker-Gelatt CG, Delio PJ, Sackett GP: (2004) Trisomy 16 in a pigtailed macaque (M. nemestrina) with multiple anomalies and developmental delays. Am J Mental Retardation, Jan;109(1):9-20.

Moore CM, Hubbard GB, Leland MM, Dunn BG, Best RG: (2003) Spontaneous ovarian tumors in twelve baboons: A review of ovarian neoplasias in nonhuman primates. Journal of Medical Primatology. Feb;32(1):48-56.