Cellular and Structural Biology | Research
Department of Cellular & Structural Biology

CSB Faculty Research Interests

 

Austad, Steven, Ph.D. Comparative biology of aging and animal models.

 

Bai, Yidong, Ph.D. Mitochondrial genetics, aging, cancer and mitochondrial diseases.

 

Bandyopadhyay, Abhik, Ph.D. Experimental therapeutics, mammary stem/progenitor cells and breast cancer, role of hormones in breast cancer and animal models of metastatic cancer.

 

Bishop, Alex, Ph.D. Systems biology and homologous recombination in carcinogenesis, DNA repair, functional genomics, genetic and environmental interactions, aging, carcinogenesis, animal models.

 

Cameron, Ivan L., Ph.D. Omega3 polyunsaturated fatty acids, breast cancer, colon cancer, nutrition, oxidative stress.

 

Dashnamoorthy, Ravi, Ph.D. Molecular response to oxygen in cancer, DNA damage response, Red-ox biology, Signal transduction, Drug metabolism and Cancer biomarkers.

 

Dong, Lily Q., Ph.D. Insulin and adiponectin signaling, obesity and diabetes.

 

Herman, Brian, Ph.D. Aging, osteoporosis, apoptosis, optical imaging, mitochondria, oxidative stress.

 

Keller, Charles, M.D. Mouse models of cancer and Muscle Stem Cells.

 

Klebe, Robert J., Ph.D. Cell adhesion, tissue engineering and metastasis.

 

Kraig, Ellen, Ph.D. Autoimmunity, immunity, aging and T cells, molecular, periodontitis, transcription, molecular genetics.

 

Larsen, Pamela L., Ph.D. Development and aging in C. elegans. Molecular genetics, expression analysis, functional genomics, genetic and environmental interactions and C. elegans physiology.

 

Leach, Robin J., Ph.D. Human molecular genetics, genetics of complex diseases, prostate cancer and diabetes.

 

Lechleiter, James D., Ph.D. Molecular and cellular mechanisms of protection during ischemic stress, acute brain injury and aging.

 

Moore, Charleen M., Ph.D. Comparative cytogenetics, aging, animal models, and history of anatomy.

 

Morgan, William W., Ph.D. Molecular regulation of tyrosine hydroxylase, gene expression, Parkinson's disease, oxidative stress, inflammation, dopamine.

 

Naylor, Susan L., Ph.D. MicroRNA, cancer genetics and genomics, aging, urologic cancers, animal models.

 

Oyajobi, Babatunde O., M.B., B.Ch., Ph.D. Bone metabolism and myeloma, multiple myeloma, breast cancer, animal models of cancer-induced bone diseases, experimental therapeutics, targeted transgenesis.

 

Penalva, Luiz Otavio F., Ph.D. Molecular analysis of cancer, post-transcriptional regulation, RNA binding proteins, cancer genomics, alternative splicing.

 

Pereira-Smith, Olivia, Ph.D. Cell senescence, immortalization, chromatin remodeling, replicative senescence, transcriptional regulation.

 

Pierce, Anson, Ph.D. Protein Conformation, Heat shock transcription factors, Neurodegenerative Disease, Amyotrophic Lateral Sclerosis, Protein Oxidation, Aging, Transgenic Mice, Proteomics.

 

Ran, Qitao, Ph.D. Mechanism of mitochondrial dysfunction and oxidative stress in aging and neurodegenerative diseases.

 

Rao, Manjeet, Ph.D. miRNA : Development and Cancer, Epigenetics and Cancer stem cell, Functional genomics, animal models.

 

Rebel, Vivienne, M.D., Ph.D. Molecular mechanisms of hematopoietic stem cell regulation, from development to old age.

 

Reiter, Russel J., Ph.D. Melatonin in free radical biology and oxidative stress, aging, antioxidants and the pineal gland.

 

Richardson, Arlan, Ph.D. Molecular aspects of aging, transgenic and knockout mice, oxidative stress, protein oxidation.

 

Sakaguchi, Alan Y., Ph.D. Genetics, function of cellular oncogenes and telomeres. Telomere binding proteins, role of telomeres in human disease and aging.

 

Stacy, Sue C., Ph.D. The effects of age on immunity, autoimmunity and immune tolerance.

 

Sun, LuZhe, Ph.D. Cancer biology, Signal transduction, Stem cell, Experimental therapeutics.

 

Tardif, Suzette, Ph.D. Primate models of obesity and aging. Reproductive energetics, pregnancy & lactation and maternal obesity.

 

Thompson, Brent J. , Ph.D. Mechanisms of antidepressant drug effects, SSRI mediated gene regulation, developmental impact of SSRI administration to neonatal rodents, and the role of SERT in epigenetic gene regulation.

 

Van Remmen, Holly, Ph.D. Animal models of sarcopenia, ALS and neurodegenerative disease, oxidative stress, aging, mitochondria and neurodegenerative disease.

 

Vogel, Kristine S., Ph.D. Signal transduction, tumorigenesis in the peripheral nervous system. Mouse models for nervous system tumors, Apoptosis in the sympathoadrenal lineage, DNA damage and repair in the peripheral nervous system, Regulation of Nf1 gene expression during development, Adapting innovative technologies for medical education in the basic sciences.

 

Walter, Christi A., Ph.D. Aging, cancer, and developmental defects. DNA repair, carcinogenesis, germ line mutagenesis and germ line stem cells. Genetic instability in aging.

 

Weaker, Frank J., Ph.D. Education, virtual reality, histology.

 

CSB Joint Appointed Faculty Research Interests:

Bone-targeted drugs as potential treatments for multiple myeloma, experimental therapeutics, organic chemistry.
Dahia, Patricia, M.D., Ph.D.
Neural crest tumors, genetics of cancer, molecular genetics, microarray-based gene sets, intersection of oncogenic pathways, gene discovery, cancer susceptibility.
Aging, mechanisms of telomere maintenance, Werner syndrome and cell regulation.
Bone metastases, prostate cancer, bladder cancer, animal models of cancer-induced bone diseases, experimental therapeutics, tumor suppressor genes.

 

Faculty Research Interests from other Departments and Institutions:

TGF-β signaling in tumorigenesis and pancreatic cancer, molecular biology.
Hargreaves, Ken M., DDS, Ph.D.
Pharmacology of pain and inflammation.
Modeling and analysis of biomedical images.
Metalloproteinsaes, extracellular matrix, left ventricular remodeling.
Germ cell development and differentiation, epigenetics, X-chromosome inactivation, stem cells and genetic integrity.
Glucocorticoid regulation of tyrosine hydroxylase expression, gene expression, aging.
Primate and opossum models of cardiovascular disease, Chagas disease, TB and melanoma. Interactions of immune system with tumor growth and metastasis in xenogenic transplant model.