C. Mauli Agrawal, Ph.D., P.E.
Associate Professor, Department of Orthopaedics
Director of Orthopaedic Biomaterials
Co-Director of Orthopaedic Bioengineering
|
Location: |
ANX, Room N228 |
|
Phone: |
(210) 567-6495 |
|
Fax: |
(210) 567-6504 |
|
E-mail: |
|
Research Interests:
Tissue Engineering: Development and study of biodegradable scaffolds with and without growth factor to regenerate musculoskeletal tissue. Total Joint Prostheses: Study of the wear mechanisms and wear debris related to ultrahigh molecular weight polyethylene. Fracture Mechanics of Bone: Development of new techniques to measure the susceptibility of bone to fracture as a function of age and/or disease.
Unique Technical and Clinical Research Capabilities/Instrumentation:
Gel Permeation Chromatograph, FTIR Spectroscope, Differential Scanning Calorimeter, Wear Particle Generator, Instron Tensile Tester, Wear Testing Machines
Publications:
Agrawal, C.M; Huang, D.; Schmitz, J.P.; Athanasiou, K.A.: Elevated Temperature degradation of a 50:50 copolymer of PLA-PGA. Tissue Engineering, Accepted 1997.
Agrawal, C.M.; Athanasiou, K.A.; Heckman, J.D.: Biodegradable PLA-PGA polymers for tissue engineering in orthopaedics. Materials Science Forum, Accepted 1996.
Agrawal, C. M., and Athanasiou, K.A.: A new technique to control the pH in the vicinity of biodegrading PLA-PGA implants. Journal of Biomedical Materials Research (Applied Biomaterials), 38(2): 105-114, 1997.
Schmitz, J.P.; Zardeneta, G.; Agrawal, C.M.; Lee, T.; Athanasiou, K.A.; Milam, S.B.: Interfacial reactions occuring during protein binding to polylactide-polyglycolide copolymers. Tissue Engineering, Accepted, 1997.
Wang, X., Agrawal, C.M.: Interfacial fracture toughness of bone-biomaterial systems. Journal of Biomedical Materials Research (Applied Biomaterials), 38(l): 1--10, 1997.
Agrawal, C.M.; Pennick, A.; Schenck, R.C.: Porous coated titanium implant impregnated with a biodegradable protein delivery system. Journal of Biomedical Materials Research (Applied Biomaterials), 36(4): 516-521, 1997.
Singhal, A.R.; Agrawal, C.M.; Athanasiou, K.A.: Salient degradation features of a 50:50 PLA/PGA scaffold for tissue engineering. Tissue Engineering, 2(3): 197-207, 1996.
Wang, X.; Subramanian, A.; Agrawal, C.M.: A comparison of different techniques for testing bone-biomaterial interfacial strength. Journal of Biomedical Materials Research (Applied Biomaterials), 33(3): 133-138, 1996.
Key Words
Orthopaedic biomaterials, biodegradable, wear, fracture