Research Interests:

Bone Morphogenetic Protein and Their Expression

Cell Line Derivation from Transgenic Mice

Feng JQ, Harris MA, Cooney AJ, Tsai MJ, Chen D, Dallas S, Tsai SY, Feng M, Mundy GR, Harris SE. The mouse bone morphogenetic protein-4 gene: Analysis of promoter utilization in fetal rat calvarial ohs and regulation by COUP-TFI orphan receptor. J Biol Chem 270:28364-28373, 1996.

Ghosh-Choudhury N, Windle JJ, Koop B, Harris MA, Guerrero DL, Wozney JM, Mundy GR, Harris SE. Immortalized murine osteoblasts derived from BMP 2-T-Antigen expressig transgenic mice. Endocrinology 137:331-339, 1996.

Ghosh-Choudhury N, Harris M, Wozney J, Mundy GR, and Harris SE. Clonal Osteoblastic cell lines from p53 Null mouse calvariae are immortalized and dependent on bone morphogenetic protien2 for mature osteoblastic phenotype. Biochem Biophys Res Commun 231:196:202, 1996.

Chen D, Dallas S, Feng JQ, Chen H, Morlyama K, Ghosh-Choudhury N, Feng M, Harris MA, Boyce BF, Mundy GR, Harris SE. Recombinant BMP 2 stimulates BMP 3 and BMP 4 mRNA in primary fetal rat calvarial cells. Calif Tissue Int 60:283-290, 1997.

BMPs, Gene Structure and Regulation, Transgenic Mice