Microbiology & Immunology Graduate Student
B.S. Microbiology - University of Texas at Austin Austin, TX 2004-2009
Post-Baccalaureate Baylor College of Medicine - Houston, TX 2009-2010
PhD Microbiology - Univ. of Texas H.S.C. at San Antonio - San Antonio, TX 2010-Present
I am currently a fourth year Ph.D. Candidate in the Department of Microbiology and Immunology working in the laboratory of Dr. Carlos J. Orihuela Ph.D. My project is focused on investigating the interactions between Streptococcus pneumoniae (the pneumococcus)and cardiomyocytes during invasive pneumococcal disease (IPD). Previously, I have implicated the pneumococcal surface adhesin choline-binding protein A (CbpA) and the host platelet activating factor (PAFr) in cardiac tissue invasion, and lesion formation. Current studies are focus on the molecular mechanism(s) responsible for cardiomyocyte death as a result of these interactions.
2009 Trainee, Human Genome Sequencing Center (HGSC)-Genetics/Genomics Research Education and Training (GREAT) Summer Research Program, BCM, Houston, TX.
2009-2010 Trainee, HGSC-Post Graduate Education Training (PGET), Post-Baccalaureate Program, BCM, Houston, TX.
2013 Travel Award to the 2013 American Society for Microbiology (ASM) General Meeting. Denver, CO.
2013-Present Translational Science Training (TST) Fellow - UTHSCSA.
2013-Present Ruth L. Kirschstein National Research Service Award (F-31) Predoctoral Fellow - NRSA
Patents UTHSCSA (May 2013)
Co-Inventor: YLN, a CbpA/Pneumolysin conjugate vaccine for protection against cardiac damage incurred during invasive pneumococcal disease.
- Armand O. Brown1, Beth Mann6, Geli Gao6, Restrepo Marcos2, Ganesh Halade2, Eric Mortensen3, Merry Lindsey2, Martha Hanes5, Elaine Tuomanen6, Carlos J. Orihuela1. The pneumococcal surface adhesin CbpA mediates cardiac microlesion formation during severe invasive pneumococcal disease. Manuscript in preparation. (To be submitted Fall 2013)