Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma
This trial looks at how well rituximab and combination chemotherapy with or without lenalidomide work to treat newly diagnosed stage II-IV diffuse large B cell lymphoma. Monoclonal antibodies, like rituximab, may interfere with the ability of cancer cells to grow and spread. Chemotherapy drugs like cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone, work in different ways to keep cancer cells from growing and spreading. Lenalidomide may work with the immune system to stop cancer cells from growing.