Diako Ebrahimi, Ph.D.
Assistant Professor, Microbiology, Immunology & Molecular Genetics, Texas Biomedical Research Institute, UTSA Biology
Dr. Ebrahimi leads a cross-disciplinary quantitative biology program. His lab combines data and expertise across multiple quantitative and experimental science disciplines such a genetics, virology, cancer, evolution, bioinformatics, mathematics, and statistics to develop and test novel hypotheses. Current studies in Dr. Ebrahimi’s lab focus on identification and quantification of molecular processes in viral and cancer immunity and evolution.
Examples of projects and questions:
- Population-specific virus-host interaction mechanisms – Why are immune genes such as APOBEC3 enzymes differently expressed in different human populations? Do these differences play a role in the interaction between our immune system and viruses such as HIV-1, HPV, SARS-CoV-2?
- Genetic and mechanistic basis of antiviral and cancer immunity – Why do the rate and severity of infectious diseases and cancer vary in different humans? What are the viral and host contributing factors?
- Quantitative biology methods and tools to deconvolute the signatures of complex biological processes – What are the sources of cancer mutations and gene expression variation in cancer? How many dysregulated processes are present in a given tumor tissue biopsy? Is viral infection a player in cancer initiation and/or evolution?
Research Area/Field of Study: Quantitative Biology, Biomedical informatics
Specific Field of Study: Viral and Cancer genomics, Evolution
Relevant Diseases: Infectious diseases (HIV, HPV, Coronaviruses, …), Cancer
Research Techniques: Bioinformatics, Next generation sequencing, Signal processing, Deep learning, Spectroscopy
Scroll table right to view more
Ph.D., Chemometrics, UNSW Australia, 2007
M.Sc., Analytical Chemistry and Chemometrics, Razi University, 2001
B.Sc., Pure Chemistry, Shahid Chamran University, 1999