Yogesh Gupta, Ph.D.

Assistant Professor

Our studies seek to provide a complete and coherent picture of human mRNA modification complexes at the molecular and atomic level with a final goal to develop novel anticancer therapeutics targeting the RNA methylome and other nucleoprotein assemblies. We employ leading-edge structural biology methods such as fX-ray crystallography, NMR, SAXS, EM in combination with an array of other biophysical and chemical biology tools to elucidate structures and mechanisms of macromolecular complexes central to childhood malignancies.

Related Diseases: Pediatric cancers

Techniques:  X-ray crystallography, NMR spectroscopy, small-angle X-ray scattering (SAXS) and other solution biophysics methods