Dr. Cole’s lab studies the genetic risk for developing common, complex diseases. She collaborates on genetic studies of minority population groups that have very high rates of metabolic and other diseases yet
are traditionally under-represented in genetic and medical research, especially when looking at how genetic risk factors affect disease and are modified according to ancestral backgrounds and environmental risk factors. Studies mainly use a family-based study design with multigenerational pedigrees, providing rich datasets for identification
of rare and population-specific inherited effects. Previous and ongoing research has generated molecular genetic data using samples from these population group.
Diseases Associated: type 2 diabetes, cardiovascular disease, metabolic disease, fatty liver disease, chronic kidney disease
Techniques Used: genomics, epigenetics, transcriptomics, genetic analysis, quantitative genetics
Sub Field of Study: health disparities