Marc D Feldman, M.D.

Dr. Marc Feldman is working on developing novel instrumentation in collaboration with faculty at the School of Engineering at the University of Texas in Austin. These instruments are often commercialized for use in animals and patients including Admittance to measure left ventricular pressure volume relations, and Optical coherence tomography to determine the composition of atherosclerotic plaques.

• Professional Background

  Education

  • 1987 - Postdoctoral Fellowship - Clinical and Research Fellow in Cardiology - Beth Israel Hospital, Harvard Medical School
  • 1984 - Residency - Medicine - Billings Hospital, University of Chicago
  • 1982 - Residency - Medicine - Billings Hospital, University of Chicago
  • 1981 - MD - Medicine - University of Pennsylvania School of Medicine
  • 1977 - BS - Zoology (Magna cum laude) - Duke University

  Appointments

  • 9/2017 - Director, Cardiac Care Unit and Director - University of Texas Health Science Center at San Antonio, Medicine, San Antonio
  • 9/2017 - Janey and Dolph Briscoe Distinguished Chair in Cardiovascular Research - UT Health San AntonioSan Antonio
  • 1/2012 - Clayton Established Investigator - Clayton Foundation for Biomedical ResearchHouston
  • 9/2007 - Professor of Medicine & Engineering, Division of Cardiology - University of Texas Health Science Center San Antonio, Medicine, San Antonio
  • 7/1998 - Staff Physician - South Texas Veterans Health Care System, Audie L. Murphy VA Hospital, Medicine, San Antonio
  • 7/1998 - Adjunct Professor School of Biomedical Engineering - University of Texas at Austin, Biomedical Engineering, Austin
  • 6/1998 - Adjunct Professor of Biomedical Engineering and Adjunct Professor - University of Texas at San Antonio (UTSA)San Antonio
  • 1/1998 - Coordinator, Cardiac Catheterization Conference - University of Texas Health Science Center San Antonio, Medicine, San Antonio

• Research & Grants

  Development of novel biomedical devices with applications in Cardiology 

  Diseases Associated: Cardiology

  Technique's Used: Optics and Electrical Engineering

  Grants

  Federal

  Funding Agency NIH Title Implantable Cardiac Power Generation Using Flexible 3D Porous This Films Status Active Period 10/2016 - 9/2021 Role Co-Investigator Grant Detail We will design, characterize, optimize and test flexible porous polymer film power generators that convert cardiac motion into electrical power to recharge automatic implantable cardiac defibrillators (AICD). Funding Agency NIH R01 Title LV SV Using Admittance Hemodynamically Unstable Arrhythmia Detection Status Active Period 4/2015 - 3/2019 Role Principal Investigator Grant Detail Develop a SV detector on previously implanted AICD leads Funding Agency NIH Title Wireless System for Ambulatory Rodents to Measure Pressure and Volume in the Left Ventricle Status Active Period 6/2017 - 4/2018 Role Co-Investigator Grant Detail Develop telemetric LV PV system

  Private

  Funding Agency Clayton Foundation for Research Title Use of light to predict and prevent future heart attacks and strokes Status Active Period 1/2012 - 12/2019 Role Principal Investigator Grant Detail Develop commercial uses of OCT

• Publications

  Abstract

  Marc D. Feldman MD, Andrew G. Gabe BSBE, Taylor Hoyt BA, Xiao Yang BS, Randal D. Robinson MD, Jessica E. McLaughlin MD, Arnold D. Estrada PhD, Thomas E. Milner PhD, Philip T. Valente MD, Bryan Cox MD. Determination of the Optical Properties of Endometriosis for Improved Detection; 2018 May. (21st Annual Medicine Research Day UT Health San Antonio). Marc D. Feldman MD, Sandeep Sagar, MD, Patricia Escobar, Meagan Oglesby, Danny Escobedo, Sander Hacker DVM, Jonathan W. Valvano PhD. Admittance Derived Stroke Volume for Hemodynamically Unstable Arrhythmia Detection; 2018 May. (21st Annual Medicine Research Day UT Health San Antonio). Feldman MD, M Hasoon, MD. Comparing Ticagrelor and Aspirin With Clopidogrel and Aspirin in Patients With Peripheral Arterial Disease: Thrombus Burden Assessed by Optical Coherence Tomography; 2018 Mar. (American College of Cardiology?s 67th Annual Scientific Session & Expo Orlando, Florida March 2018). M. Feldman, T. Hoyt, T. Milner, M. Buja, A. McElroy, D. Vela, V. Baruah. Optical Coherence Tomography Virtual Histology of Coronary Arteries; 2017 Nov. (Transcatheter Cardiovascular Therapeutics (TCT) Symposium Denver, Colorado Oct 30- Nov 7, 2017). Marc D. Feldman MD, Xiao Yang BS. Impact of Ticagrelor and Aspirin verses Clopidogrel and Aspirin in Symptomatic Patients with Peripheral Arterial Disease (PAD): Thrombus Burden Assessed by Intravascular Optical Coherence Tomography; 2016 Oct. (Society for Cardiovascular Angiography and Interventions conference New Orleans, LA , May 2017). Phipps J, Hoyt T, Vela D, Buja L, Milner T, Feldman MD. Effects of light scattering on the diagnosis of thin-capped fibroatheromas in optical coherence tomography images: Optics in Cardiology, Rotterdam, the Netherlands 2015; 2015 Jan. (Optics in Cardiology, Rotterdam, the Netherlands 2015). Hoyt T, Phipps J, Vela D, Wang T, Buja L, Jang IK, Milner T, Feldman MD. Diagnosis of thin-capped fibroatheromas in intravascular optical coherence tomography images: effects of light scattering: American Heart Association Scientific Sessions Orlando, FL 2015; 2015 Jan. (American Heart Association Scientific Sessions Orlando, FL 2015). Hoyt T, Phipps J, Vela D, Buja L, Milner T, Feldman MD. Mechanisms for False Thin Cap Fibroatheromas Identified by Optical Coherence Tomography: Transcatheter Cardiovascular Therapeutics Washington, DC 2015; 2015 Jan. (Transcatheter Cardiovascular Therapeutics Washington, DC 2015). Minami Y, Phipps J, Hoyt T, Ong D, Vergallo R, Feldman MD, Jang IK. Increased Superficial Bright Spots at the Culprit Lesion in Patients with Acute Coronary Syndrome: An Optical Coherence Tomography Study: American College of Cardiology Scientific Sessions, San Diego, CA 2015; 2015 Jan. (American College of Cardiology Scientific Sessions, San Diego, CA 2015). Hoyt T, Cilingiroglu M, Kotsia A, Rangan B, Banerjee S, Phipps J, Feldman MD, Brilakis E. Optical Coherence Tomography Evaluation of Aortocoronary Bypass Grafts During the First Year After Coronary Artery Bypass Graft Surgery: Insights from the Cardiac Catheterization for Bypass Graft Patency Rate Optimization (CABG-PRO) study: Society for Cardiovascular Angiography and Interventions conference San Diego, CA 2015; 2015 Jan. (Society for Cardiovascular Angiography and Interventions conference San Diego, CA 2015).

  Journal Article

  Gupta AK, Feldman MD. Fractional flow reserve in non-culprit vessel during ST-segment elevation myocardial infarction: reliable or prone to error? JACC Cardiovasc Interv 2018 May;11(8):725-727. Yang X, Leesar M, Ahmed H, et al, Feldman MD, Cilingiroglu M. Impact of Ticagrelor and Aspirin verses Clopidogrel and Aspirin in Symptomatic Patients with Peripheral Arterial Disease Cardiovascular Revascularization Medicine 2018 Feb;10(1016):02-013. Feldman MD, Milner TE. Improved plaque classification with Optical Coherence Tomography JACC CV Imaging 2017 Dec;10(1016):007-011. Haines DE, Wong W, Canby R, Jewell C, Houmsse M, Pederson D, Sugeng L, Porterfield J, Kottam A, Pearce J, Valvano J, Michalek J, Trevino A, Sagar S, Feldman MD. Validation of a Defibrillation Lead Ventricular Volume Measurement Compared to 3D Echocardiography Heart Rhythm 2017 Jun;10(1016):1515-1522. Halaney DL, Sanyal A, Nafissi NA, Escobedo D, Goros M, Michalek JE, Acevedo PJ, Perez W, Escobar GP, Feldman MD, Han HC. The Effect of Trabeculae Carneae on Left Ventricular Diastolic Compliance: Improvement in Compliance With Trabecular Cutting Journal of Biomechanical Engineering 2017 Jan;139(3). Yoshiyasu Minami, Taylor Hoyt, Jennifer E. Phipps, Thomas E. Milner, Lei Xing, Hang Lee, Bo Yu, Marc D. Feldman, Ik-Kyung Jang. Lipid-lowering therapy stabilizes the complexity of non-culprit plaques in human coronary artery: a quantitative assessment using OCT bright spot algorithm Int J Cardiovasc Imaging 2016 Dec;33(2017):453-461. Phipps JE, Hoyt T, Vela D, Wang T, Michalek JE, Buja LM, Jang IK, Milner TE, Feldman MD. Diagnosis of Thin-Capped Fibroatheromas in Intravascular Optical Coherence Tomography Images: Effects of Light Scattering Circulation: Cardiovascular Interventions 2016 Jul;9(7):1-12. Feldman MD, Minami Y, Phipps JE, Hoyt T, Milner TE, Ong DS, Soeda T, Vergallo R, Jang Ik. Clinical utility of quantitative bright spots analysis in patients with acute coronary syndrome: an optical coherence tomography study Int J Cardiovasc Imaging 2015 Dec;. Feldman MD, Halaney DL, Zahedivash A, Phipps JE, Wang T, Dwelle J, Saux CJ, Asmis R, Milner TE. Differences in forward angular light scattering distributions between M1 and M2 macrophages J Biomed Opt 2015 Nov;. Feldman MD, Yin B, Dwelle J, Wang B, Wang T, Rylander HG 3rd, Milner TE. Fourier Optics analysis of phase-mask based path-length-multiplexed optical coherence tomography J Opt Soc AM A Opt Image Sci Vis 2015 Nov;. Feldman MD, Wang T, McElroy A, Halaney D, Vela D, Fung E, Hossain S, Phipps J, Wang B, Yin B, Milner TE. Detection of plaque structure and composition using OCT combined with two-photon luminescence (TPL) imaging Lasers Surg Med 2015 Aug;. Feldman MD, Jo JA, Park J, Pande P, Shresta S, Serafino MJ, Rico Jimenez Jde J, Clubb F, Walton B, Buja LM, Phipps JE, Adame J, Applegate BE. Simultaneous morphological and biochemical endogenous optical imaging of atherosclerosis Eur Heart J Cardiovase Imaging 2015 Aug;. Feldman MD, Phipps JE. Can Multimodal Invasive Imaging Be Used to Predict Periprocedural Myocardial Infractions? JACC Cardiovasc Interv 2015 Jun;. Feldman MD, Wang T, McElroy A, Halaney D, Vela D, Fung E, Hossain S, Phipps J, Wang B, Yin B, Milner TE. Dual-modality fiber-based OCT-TPL imaging system Biomed Opt Express 2015 Jan;. Feldman MD, Mancuso JJ, Halaney DL, Elahi S, Ho D, Wang T, Ouyang Y, Dijkstra J, Milner TE. Intravascular optical coherence tomography light scattering artifacts: merry-go-rounding, blooming, and ghost struts J Biomed Opt 2014 Dec;. Larson, Erik R, Porterfield, John E., Marmol-Velez, Juan, Panday, Manoj, Sagar, Sandeep, Escobedo, Daniel, Michalek JE, Ouyang, Yongjian, Valvano, Jonathan, Pearce, John A, Feldman MD. Admittance to Detect Alterations in Left Ventricular Stroke Volume Heart Rhythm 2014 Nov;11(11):2075-2083. Feldman MD, Elahi S, Milner TE, Rapoza RJ, Dijkstra J. Flare spots in intravascular optical coherence tomography images of bioabsorbable stents JAAC Cardiovasc Imaging 2014 Nov;. Marmagkiolis K, Lendel V, Cawich I, Leesar M, Feldman MD, Cilingiroglu M. Optical coherence tomography to guide below-the-knee endovascular interventions Int J Cardiol 2014 Oct;176(3):1336-1338. Marmagkiolis K, Lendel V, Leesar MA, Feldman MD, Cilingiroglu M. Use of optical coherence tomography during superficial femoral artery interventions J Invasive Cardiol 2014 May;26(5):220-223.

• Clinical

  Board Certifications

  • American Board of Internal Medicine/Interventional Cardiology
  • American Board of Internal Medicine/Cardiovascular Disease