Director of Research
Department of Oral & Maxillofacial Surgery
Dr. Nathan Jeske's lab conducts research on signaling mechanisms that mediate inflammatory pain and analgesia. Over 100 million Americans suffer from pain annually, and understanding how this sensation graduates to a chronic state, as well as how to treat it efficaciously, are the primary research goals of the Jeske lab. Research in the Jeske lab focuses on biochemical signaling molecules and pathways unique to pain-sensing neurons in the periphery that can be targeted to reduce pain, increase analgesia, and improve the quality of life for pain patients. Researchers combine molecular, biochemical, pharmacological, physiological, and behavioral studies with opportunities for human clinical expertise to provide comprehensive approaches to some of our most important issues related to pain and analgesia in our current society.