Angélica Olmo-Fontánez, M.S.

Publications

• Olmo-Fontánez A.M., Scordo J.M., Garcia-Vilanova A., Maselli D.J., Peters J., Restrepo, B.l., Clemens D.L., Turner J., Schlesinger L.S., and Torrelles J.B. (2022) Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis growth in alveolar epithelial cells and bacterial translocation into the cytosol. [BioRxiv Pre-print May, 2021: BIORXIV/2021/443884]

• Olmo-Fontánez A.M. and Turner J. (2022) Tuberculosis in an Aging World. Pathogens 2022, 11, 1101. https://doi.org/10.3390/pathogens11101101  

• Scordo J.M., Piergallini T.J., Olmo-Fontánez A.M., et al. (2022) Recall responses in the lung environment are impacted by age in a pilot study of Mycobacterium bovis-BCG vaccinated rhesus macaques. Exp Gerontol. 2022 Oct 1;167:111904. https://doi.org/10.1016/j.exger.2022.111904

• Garcia-Vilanova A. Olmo-Fontánez A.M., Moliva J.I., Allué-Guardia, A., Harjinder S., Merrit R.E., Caceres, D., Peters J., Restrepo, B., Wang, Y., Schlesinger L.S.,  Turner J., Weintraub S.T., Torrelles J.B. (2022) The aging lung mucosa: A proteomics study. The Journals of Gerontology: Series A, 2022;, glac091. https://doi.org/10.1093/gerona/glac091 

• Allué-Guardia A., Garcia-Vilanova A. Olmo-Fontánez A.M., Peters J., Maselli D.J., Turner J., Schlesinger L.S., and Torrelles J.B. (2022) Host-and age-dependent transcriptional changes in Mycobacterium tuberculosis cell envelope biosynthesis genes after exposure to human alveolar lining fluid. International Journal of Molecular Sciences. 23(2):983. https://doi.org/10.3390/ijms23020983  

• Olmo-Fontánez A. M., Scordo J. M., Garcia-Vilanova A., Maselli-Caceres D., Peters J., Clemens D., Turner J., Schlesinger L. S., and Torrelles J. B.  (2021) Effect of the elderly human lung mucosa on Mycobacterium tuberculosis infection of the alveolar epithelium. J Immunol. 206 (1 Supplement) 65.07.

• Olmo-Fontánez A.M. and Torrelles J.B. (2021) Alveolar Epithelial Cells. In: Karakousis P.C., Hafner R., Gennaro M.L. (eds) Advances in Host-Directed Therapies Against Tuberculosis. Springer, Cham. https://doi.org/10.1007/978-3-030-56905-1_16

• Singh D.K., Singh B., Ganatra S.R., Gazi M., Cole J., Thippeshappa R., Alfson K.J., Clemmons E., Gonzalez O., Escobedo R., Lee T.H., Chatterjee A., Goez-Gazi Y., Sharan R., Gough M., Alvarez, C., Blakley A., Ferdin F., Bartley C., Staples H., Parodi L., Callery J., Manino A., Klaffke B., Escareno P., Platt R., Hodara V., Scordo J., Gautam S., Vilanova A.G., Olmo-Fontánez A.M., et al. (2021). Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets. Nature Microbiology 6, 73–86. https://doi.org/10.1038/s41564-020-00841-4

• Oladunni F.S., Park JG., Pino P.A. Gonzalez O., Akhter A., Allué-Guardia A., Olmo-Fontánez A.M., et al. (2020). Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice. Nature Communications 11, 6122. https://doi.org/10.1038/s41467-020-19891-7

• Moliva JI, Duncan MA*, Olmo-Fontánez A.M.*, Akhter A, Ault R, Sasindran SJ, Reinhold-Larsson N, Rajaram MVS, Merrit RE, Lafuse WP, Zhang L, Wang S-H, Beamer G, Wang Y, Turner J, Schlesinger LS, Torrelles JB (2019). Declining innate host defense functions of the lung mucosa in the elderly drives host susceptibility to Mycobacterium tuberculosis infection. Journal of Infectious Diseases, 220:514-523. https://doi.org/10.1093/infdis/jiz138

• Scordo JM, Olmo-Fontánez A.M., Kelley HV, Sidiki S, Arcos J, Akhter A, Wewers MD, and Torrelles JB (2019). The Human Lung Mucosa Drives Differential Mycobacterium tuberculosis Infection Outcome in the Alveolar Epithelium. Mucosal Immunology, 12:795–804 https://doi.org/10.1038/s41385-019-0156-2