Sarah is a first-year graduate student in the South Texas Medical Scientist Training Program under the mentorship of Dr. Ann Griffith. Her previous research experience is in the field of G protein-coupled receptor (GPCR) signaling, where she studied the signaling mechanisms of CXCR4 and CXCR5, two chemokine receptors implicated in many cancers. Her current research focuses on investigating the role of paracrine mTOR signaling in the thymus and the effects of aging on thymic stromal architecture and T cell immunity. She is currently interested in pursuing residency in pediatrics and medical genetics.
Wedemeyer MJ, Mahn SA, Getschman AE, Crawford KS, Peterson FC, Marchese A, McCorvy JD, Volkman BF. The chemokine X-factor: structure-function analysis of the CXC motif at CXCR4 and ACKR3. 2020 October; Journal of Biological Chemistry; 295, 13927-13939.
Caballero A, Mahn SA, Ali MS, Rogers MR, Marchese A. Heterologous regulation of CXCR4 lysosomal trafficking. 2019 May; Journal of Biological Chemistry; 294, 8023-8036.
English JE, Mahn SA, Marchese A. Endocytosis is required for CXC chemokine receptor type 4 (CXCR4)-mediated Akt activation and antiapoptotic signaling. 2018 July; Journal of Biological Chemistry; 293, 11470-11480.
Anthony S. Wu Outstanding Chemistry Student Award, Mount Mary University, 2016
B.S., Chemistry, Mount Mary University, 2017