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Graduate School of Biomedical Sciences, UT Health San AntonioGraduate School of Biomedical Sciences, UT Health San Antonio

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  • Sergio Cepeda
Sergio_Cepeda

Programs

  • Ph.D. in Integrated Biomedical Sciences

IBMS Discipline

  • Molecular Immunology & Microbiology

Mentor

  • Ann V. Griffith, Ph.D.

Sergio Cepeda

Ph.D. Student

Biography

Sergio’s research interest involves the development and function of intrathymic B cells. The thymus has been traditionally thought of as an organ for T cell development but recent evidence suggests a permanent population of B cells exists as well. The purpose of these B cells is largely unknown, however, making them a new and exiting question in an old field. We have recently identified age-associated accumulation of these cells in the thymus and are working towards understanding the function and kinetics of these cells in both young and aged animals.

 

  • Publications
  • Awards

Publications

Cepeda S, Cantu C, Orozco S, Xiao Y, Brown Z, Semwal MK, Venables T, Anderson MS, Griffith AV.  Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens. Cell Rep. 2018 Jan 30;22(5):1276-1287. doi: 10.1016/j.celrep.2018.01.015. PMID: 29386114

Cepeda S, Griffith AV. Thymic stromal cells: Roles in atrophy and age-associated dysfunction of the thymus. Exp Gerontol. 2018 May;105:113-117. doi: 10.1016/j.exger.2017.12.022. Epub 2017 Dec 24. Review. PMID: 2927875

Awards

Howard Hughes Medical Institute Gilliam Fellowship, 2018

AAI Trainee Poster Award – Poster Presentation, 2018

Related Media

  • Sergio Cepeda and Dr. Ann Griffith Awarded Howard Hughes Medical Institute Gilliam Fellowship
  • MIMG’s 6 AAI Awardees
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