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Education
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| Year | Degree | Discipline | Institution |
| 1998 | Postdoctoral Fellowship | Molecular Biology | University of Texas Health Science Center at San Antonio San Antonio , TX |
| 1997 | PhD | Molecular Biology | University of Texas Health Science Center at San Antonio San Antonio , TX |
| 1986 | MD | Neuroanatomy | Fujain Medical College Fujain , China |
| 1983 | Residency | Ear, Nose and Throat | Fujian Medical College Fujian , China |
| 1982 | MD | Medicine | Fujian medical College Fujian , China |
Appointments
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| 9/2015 - Present | Professor | The University of Texas Health Science Center, Developmental Dentistry, San Antonio, TX |
| 12/2013 - Present | Adjunct Professor | Wuhan University, Dental School |
| 4/2011 - Present | Faculty Member | University of Texas Health Science Center at San Antonio, Graduate School, Physiology, San Antonio, TX |
| 9/2010 - Present | Associate Professor with Tenure | University of Texas Health Science Center at San Antonio, Developmental Dentistry, San Antonio, TX |
| 8/2009 - Present | Adjunct Faculty and Adjunct Professor | University of Texas at San Antonio (UTSA), Department of Biomedical Engineering (BME), Graduate School, TX, San Antonio, TX |
| 9/2007 - Present | Faculty Member | University of Texas Health Science Center at San Antonio, Periodontic Graduate Student Program |
| 7/2007 - Present | Faculty Member | Uiversity of Texas Health Science Center at San Antonio, Cancer Track, Graduate School of Biomedical Sciences, San Antonio, TX |
Expertise
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Androgen receptor in prostate cancer - Gene regulation of androgen receptor in prostate cancer progress |
|
Biomedical Science - Dental pulp and periodontics ligament stem cells for dental tissue repair. |
|
Dentinogenesis - Gene regulation of dentinogenesis and dentin genetic diseases |
Publications
Abstract |
| Gullard A, Wilson MB, Mamaeva O, MacDougall M, Chen S. Dentin Induction: BMP/TGFa Pathway Genes in Radicular Dentin Dysplasia Seattle, WA, USA; 2013 Jan. (91st International/American Associations for Dental Research). |
Journal Article |
| Fang Q, Yang W, Li H, Hu W, Chen L, Jiang S, Dong K, Song Q, Wang C, Chen S, Liu F, Jia W. Negative Regulation of Disulfide-bond A Oxidoreductase-like Protein (DsbA-L) Gene Expression by the Transcription Factor Sp1 Diabetes 2014 Jul;. |
| Yuan G, Zhang L, Yang G, Yang J, Wan C, Zhang L, Song G, Chen Z, Chen S. The distribution and ultrastructure of forming blood capillaries and the effect of apoptosis on vascularization in mouse embryonic molar mesenchyme Cell Tissue Res, 356:137-145 2014 Jan;. |
| Ozer A, Yuan GH, Yang GB, Wang F, Li W, Yang Y, Guo F, Gao QP, Shoff L, Chen Z, Gay I, Donly KJ, MacDougall M, Chen S. Domain of Dentine Sialoprotein Mediates Proliferation and Differentiation of Human Periodontal Ligament Stem Cells Plos One 8 (12): e81655 2013 Jan;. |
| Liu H, Lin H, Zhang L, Sun Q, Yuan G, Zhang L, Chen Z*, Chen S* *corresponding authors. MiR-145 and miR-143 regulate odontoblast differentiation through targeting Klf4 and Osx in feedback loop J Biol Chem 288; 9261-9271 2013 Jan;. |
| Wang F, Wu LA, Li W, Yang Y, Guo F, Gao Q, Chuang HH, Shoff L, Wang W, Chen S. Immortalized mouse dental papilla mesenchymal cells preserve odontoblastic phenotype and respond to bone morphogenetic protein In Vitro Cell Dev Biol Anim 49;626-637 2013 Jan;. |
| Mu Y, Xu Z, Contreras C, McDaniel JS, Donly KJ,Chen S. Mutational Analysis of AXIN2, MSX1 and PAX9 in Two Mexican Oligodontia Families Genet. Mol. Res. 12(4); 4446-4458 2013 Jan;. |
| Mu Y, Xu Z, Contreras CI, McDaniel JS, Donly KJ, Chen S . Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia Genet Mol Res 2012 Sep;11(4):4110-4120. |
Teaching
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| Date | Description | Institution | # Students |
| 7/2014 - Present | Post-Doctoral Student Supervision | Fujian Medical University, China | |
| 11/2013 - Present | Post-Doctoral Student Supervision | Zhejiang University, China | |
| 8/2012 - Present | Masters' Thesis Directed | Periodontics Graduate Program, UTHSCSA | |
| 4/2012 - Present | Post-Doctoral Student Supervision | UTHSCSA | |
| 2/2012 - Present | Post-Doctoral Student Supervision | Peking University | |
| 2/2012 - Present | Ph.D. Dissertations Directed | ||
| 1/2012 - Present | Post-Doctoral Student Supervision | UTHSCSA | |
| 7/2011 - Present | Post-Doctoral Student Supervision | Gazi Univ. Turkey | |
| 7/2010 - Present | Masters' Thesis Directed | University of Texas Health Science Center at San Antonio | |
| 3/2010 - Present | Post-Doctoral Student Supervision | UTHSCSA | |
| 3/2010 - Present | Pediatric Dentistry | The University of Texas Health Science Center | |
| 9/2009 - Present | Biomedical Core Course Dentinogenesis | ||
| 30 residents, one hour lecture | |||
| 7/2008 - Present | Post-Doctoral Student Supervision | ||
| 3/2008 - Present | Development of Dentition | The University of Texas Health Science Center | |
| 9/2006 - Present | Biomedical Core Course Craniofacial Development | ||
| 6/2005 - Present | Investigative Project | ||
Grants
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| Funding Agency | Natural Science Foundation of China (Major International Regional ) Joint Research |
| Title | The epigenetic regulation of dentinogenesis defect in Bmp2 deficient mice. |
| Status | Active |
| Period | 1/2015 - 12/2019 |
| Role | Co-Investigator |
| Grant Detail | The major goal of this project is to investigate how BMP2 regulates coding and non-coding gene expression during tooth development, in particular dentin formation. |