Mingjun Bi, Ph.D.

• Professional Background

  Education

  • 2013 - PhD - Biochemistry and Molecular Biology - China Agricultural University

  Training

  • 2016 - Postdoc Fellow - Cancer epigenetics and gene regulation - The University of Texas Health Science Center at San Antonio
  • 2013 - Postdoc Fellow - Tumor Biology - University of Cincinnati College of Medicine

• Research & Grants

  My long-term research seeks to understand the molecular & epigenetic mechanisms of signal-regulated gene expression in the development of cancer and other diseases. We make extensive use of a set of integrated biochemical, genomics and molecular oncology approaches to tackle the broad and critical questions on the topic of gene regulation and cancer. 

• Publications

  • Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer
  • A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer
  • Enhancer RNAs mediate estrogen-induced decommissioning of selective enhancers by recruiting ERα and its cofactor