Higher-Dose Radiation Therapy versus Standard Radiation Therapy as Treatment for Early Stage Breast Cancer
The purpose of this study is to determine whether one type and schedule of radiation following lumpectomy will be at least as good as another type and schedule of radiation as treatment for preventing the cancer from coming back in patients diagnosed with early-stage breast cancer. The primary objective is to identify if one radiation regimen is as good as another radiation regimen in preventing the cancer from coming back in the area of the breast. The study will enroll 2,312 participants from many cancer centers in the US and Canada. In addition to other conditions for enrollment, women are enrolled within 50 days of completing surgical removal of the breast cancer. Patients with a history of certain types of heart problems, liver problems, chronic infections, pre-existing skin problems, or lupus may not be eligible.