HepaSphere/Quadrasphere Microspheres for Delivery of Doxorubicin for the Treatment of Hepatocellular Cancer
A research study of cancer in the liver that may be treated with a procedure called transarterial chemoembolization (TACE). In this procedure a chemotherapy drug is mixed with a kind of oil and injected into the artery that supplies blood to the tumor, and then tiny particles are injected that block the blood flow and help keep the chemotherapy in the tumor. The injection of chemotherapy into the hepatic artery (artery that goes into the liver) for the purposes of treating hepatocellular carcinoma (the type of liver cancer that you have been diagnosed with) has been used for over 20 years, and is considered the standard of therapy for your condition. The particular type of chemotherapy (doxorubicin) is used to treat many types of cancers. The intent of this study is to examine the effectiveness of a new type of particle that may increase the efficacy of the chemoembolization procedure by retaining the chemotherapy within the tumor for a longer time. In addition, the use of this particle may result in decreased side effects from the chemotherapy itself, by slowing down the release of the chemotherapy into the bloodstream.