A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Free Fatty Acid Supplementation on Breast Cancer (CTMS# 16-0119)
Assess the impact of dietary omega 3 FFA:
Serum CSF-1 levels
patient serum-induced expression of PGE2 by neoplastic mammary epithelial cells, OM3/OM6
circulating levels of pro-inflammatory cytokines (i.e. IL-6, TNF- , IGF-1), steroids (i.e. estrogen and testosterone) and lipids (omega-6 and omega-3 PUFAs)
Tissue expression of aromatase, CSF1/CSF1R and infiltrating macrophage number and polarity.