The overarching goal of the Texas Hepatocellular Carcinoma Consortium (THCCC), funded by CPRIT Multiple Investigator Research Award (MIRA), is to reduce the burden and mortality of hepatocellular cancer (HCC) in Texas.
The purpose of this project is to establish a high-quality repository of male and female genitourinary tissue specimens with an associated database of relevant clinical, follow-up and outcome data. Development and maintenance of a high-quality repository is essential to the conduct of translational research for genitourinary cancer. When possible, specimens will be accrued by freezing fresh excess tissue removed at surgery or biopsy. No extra tissue will be removed during surgery expressly for the repository. Specimens will also be obtained from archival paraffin-embedded tissue. Clinical data will be obtained from tumor registry files, from subjects, or review of medical records.
To create a Spanish version of the Pediatric Nausea Assessment Tool (PeNAT) for assessment of chemotherapy-induced nausea severity with face validity among Hispanic American children receiving cancer chemotherapy.
To evaluate the longitudinal CA-125 algorithm for the early detection of ovarian cancer in a low risk cohort of women.