Mary Salazar has worked in oncology for more than 20 years. She began her profession at Johns Hopkins Hospital in Baltimore, Maryland, where she practiced for more than seven years. She then relocated to The University of Texas M.D. Anderson Cancer Center in Houston, Texas, where she was employed for 11 years. She moved to San Antonio in 2007 and worked in private practice until 2012. She transitioned to the Mays Cancer Center within the department of medical oncology. She specifically works with gastrointestinal and genitourinary malignancies.