Skip to main content

Part of UT Health San Antonio

School of Dentistry, UT Health San AntonioSchool of Dentistry, UT Health San Antonio

Part of UT Health San Antonio

Institutional Core Labs

  • iLabs
  • Bioanalytics & Single-Cell
  • Biospecimen and Translational Genomics
  • Flow Cytometry
  • Mass Spectometry
  • Optical Imaging
  • Structural Biology (NMR)
  • Structural Biology (X-Ray Crystallography)

Find a Researcher

  • Profiles

Research by School

  • Long School of Medicine
  • School of Dentistry
  • School of Health Professions
  • School of Nursing

Software Training & Cyberinfrastructure

  • VPR IT

Additional Resources

  • Environmental Health & Safety
  • Council of Principal Investigators
  • National Academy of Inventors
  • Office of Technology Commercialization
  • Postdoc Positions
  • Report A Discovery
  • Research Directory
  • San Antonio Bioscience Research
  • San Antonio Partnership for Precision Therapeutics
  • Spotlight on Research Integrity

Close Quicklinks

Menu
  • Home
  • About
  • Research Topics
  • Researchers
  • Clinical Trials
  • School of Dentistry
  • Patient Care

You are here

  • Clinical Trials
  • Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots

Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots

This multi-center exploratory clinical trial is a randomized trial designed to test whether a regenerative endodontic procedure using tissue engineering principles (REGENDO), or a revascularization (REVASC) endodontic procedure, in comparison to standard apexification treatment using a mineral trioxide aggregate barrier (apexification; APEX), produces a significantly better composite clinical outcome for the treatment of immature permanent teeth with pulpal necrosis.

About this Study

Clinical Trial | UT Health San Antonio

Qualifications

  • Is the participant between the ages of 6 and 20?
  • Can you travel to one of the study locations (San Antonio, Texas; Baltimore, Maryland; Loma Linda, California) for treatment and follow-up?
  • Does an endodontist consider the tooth in question restorable without the need of a stainless steel crown?
  • Do you have access to a telephone and the ability to read and comprehend study materials in English or Spanish?
  • Is there a legal guardian willing and able to provide informed consent?

See if I qualify

Participating in this Study

  • Choosing to participate in a study is an important personal decision.
  • Talk with your doctor and family members or friends about deciding to join a study.
  • To learn more about this study, you or your doctor may contact the study research staff.
  • Please refer to this study by its ClinicalTrials.gov identifier: NCT01976065

Participate today

About the Researchers

Dr. Ken Hargreaves and Dr. Anibal Diogenes are well-known experts in the field of endodontics. Their past collaborations have lead to groundbreaking therapies, which have allowed pediatric patients to keep damaged teeth that would have otherwise had to be removed due to dental trauma. 

The American Association of Endodontists Foundation

AAE logo This clinical trial is funded by a $1.7 million grant from the American Association of Endodontists Foundation. Additional support is supplied by the UT Health Science Center School of Dentistry.

American Association of Endodontists Foundation

Map image of UT Health San Antonio location

Looking for Patient Care?

UT Health San Antonio
School of Dentistry

7703 Floyd Curl Drive
San Antonio, TX 78229

210-567-7000

  • Contact us
  • Maps & directions
  • Patient rights and responsibilities
  • Language assistance
  • Give a donation

We make lives better ®

The University of Texas Health Science Center at San Antonio, also called UT Health San Antonio, is a leading academic health center with a mission to make lives better through excellence in advanced academics, life-saving research and comprehensive clinical care including health, dental and cancer services.

Web Privacy | Links from websites affiliated with UT Health's website (uthscsa.edu) to other websites do not constitute or imply university endorsement of those sites, their content, or products and services associated with those sites. The content on this website is intended to be used for informational purposes only. Health information on this site is not meant to be used to diagnose or treat conditions. Consult a health care provider if you are in need of treatment.