Children are at risk for infections due to trauma or caries. Complete tooth development may take up to two years from the time a tooth has erupted. During this period, dental infections and subsequent dental loss have devastating long-term effects. Treatment options for young patients with infected teeth have been limited to traditional root canal treatments. Stem-cell based therapies represent a new treatment modality that promotes continued development and reestablishment of normal function.
Our research has focused on the identification of stem cells found in infected teeth in young patients and their therapeutic use. We have demonstrated that these cells can be delivered surgically during a regenerative endodontic procedure. This procedure allows for continued root development in addition to healing.